CORDIS Project
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This project investigates the interactions between neurons and glial cells using a microfluidic co-culture platform. By manipulating neuronal activity, it aims to understand glial responses and their impact on the nervous system's integrity and function, particularly in the context of neuropathic diseases and aging.
Interactions between neurons and glial cells underlie the normal development, structure and function of the nervous system.
Perturbation of this communication occurs during injury, in acquired or hereditary neuropathic diseases of the central and peripheral nervous systems, and with ageing.
However, the specific nature and the physiological significance of neuron-glia interactions remain largely unknown.
We propose here the use of a microfluidic co-culture platform to characterize and investigat…
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