CORDIS Project
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This project aims to develop a new catalytic method for synthesizing complex natural products in a single step. By transforming simple aromatic molecules into enantiopure structures, it seeks to create diverse small-molecule libraries for potential biological applications.
This proposal outlines a blueprint towards the development of a new catalytic strategy for chemical synthesis, wherein catalytic cascade processes are designed around the transformation of a common functional motif to a diversity of enantiopure natural product architectures, in a single step.
The hypothesis behind the chemo-catalytic synthesis strategy involves the development of a catalytic enantioselective dearomatization (CED) process that directly converts flat aromatic molecules into comple…
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