CORDIS Project
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cDcIVA explores the relationship between gut health and bone marrow function, specifically how retinoic acid from Vitamin A influences the development of immune cells. The project aims to enhance understanding of nutrition's role in immune system regulation.
cDcIVA aims to reveal a gut-bone marrow axis mediated by retinoic acid (RA) as a fate-instructive factor for the development of conventional dendritic cell (cDC) precursors in the bone marrow.
Communication between the intestine and other organs, such as the bone marrow is mediated by several nutrients, including Vitamin A.
This proposal focuses on examining how the Vitamin A derivative, RA, reaches the bone marrow and boosts the output of a specific RA-responsive cDC subset with implications on…
FUNDACAO D. ANNA DE SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD
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