CORDIS Project
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This study aims to uncover the mechanisms behind brain asymmetry in zebrafish, focusing on the migration of parapineal cells. It investigates how localized signaling influences cell movement and communication during this critical developmental process.
The long-term aim of the proposed study is to resolve the genetic and cell biological mechanisms that contribute to the establishment of vertebrate brain asymmetry.
In the zebrafish forebrain, an event crucial in establishing and elaborating asymmetry is the migration of the parapineal primordium.
Parapineal cells are specified bilaterally at the midline.
They subsequently assemble into a rosette-like structure and migrate to the left side of the brain.
The molecular basis of the cellular commun…
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