CORDIS Project
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This project investigates the role of cholecystokinin interneurons in regulating gamma oscillations in the prefrontal cortex, which are crucial for cognitive functions affected in schizophrenia. By employing various advanced techniques, the research aims to clarify the mechanisms underlying cognitive deficits and ident…
Dysfunction of the prefrontal cortex (PFC) contributes to cognitive deficits that represent the primary cause of disability associated with schizophrenia.
However, currently available antipsychotic medications are only minimally effective for cognitive symptoms, demonstrating the need for better therapeutic targets.
Treatments for cognitive deficits in schizophrenia remain underdeveloped in large part because the relevant physiological mechanisms remain unclear.A major hypothesis is that in schi…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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