CORDIS Project
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This project investigates how archaea, specifically Sulfolobus acidocaldarius, regulate cell division without nuclei or organelles. It employs advanced imaging techniques to explore chromosome segregation and membrane dynamics, aiming to enhance understanding of eukaryotic evolution and potential industrial application…
Archaea and eukaryotes share conserved regulators such as ESCRTIII proteins that are involved in fundamental aspects of eukaryotic cell division, a finding that assumes particular importance in the context of widely accepted models for the evolution of eukaryotes from an ancestral archaeal host.
Yet the mechanisms by which archaea regulate cell division- in the absence of nuclei, organelles and a rigid cell wall- are poorly understood.
The research programme proposed here aims to fill this gap i…
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