CORDIS Project
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This project develops new catalytic methods to control the configuration of molecules with multiple stereogenic elements, enabling the creation of complex stereoisomers. By expanding the understanding of stereochemistry, it aims to enhance organic synthesis and improve the design of bioactive compounds.
Catalytic, stereoselective methodologies to study the control over the configuration of stereogenic elements with three- four-, five- and six-fold stereoisomerism are proposed.
Previous catalyst-stereocontrolled methods allowed the differentiation of a twofold number of stereoisomers for any given stereogenic element.
It is thus anticipated that expanding the stereogenicity in stereoselective catalysis represents a significant advance for the field.
The reunification of conformational analysis a…
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