CORDIS Project
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The cassaFLOW project focuses on developing a more efficient synthesis process for non-natural amino acids, specifically isoleucine and threonine. By employing a novel cascade reaction technology, it aims to reduce the synthesis steps from eight to three, enhancing pharmaceutical production.
Non-natural amino acids are essential building blocks for pharmaceuticals.
The COVID-19 drug Paxlovid is a prime example for this.
But as for most pharmaceuticals, the synthesis of these amino acids is complex and requires many steps.
This is especially true for amino acids with 2 stereocenters, the focus of this application.
Of the group of the 20 most common natural amino acids 2 have not one but two chiral centers: isoleucine and threonine.
Non-natural isomers of these 2 amino acids are surpr…
TECHNISCHE UNIVERSITEIT DELFT
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Sweden, Umea
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
Netherlands, Den Hoorn
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
Netherlands, Eindhoven
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Germany, Bielefeld
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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