CORDIS Project
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This project aims to develop mathematical models to understand cardiotoxicity caused by kinase inhibitors, a class of cancer drugs. It integrates experimental data to identify predictive signatures that can help mitigate the risk of heart-related side effects.
Kinase inhibitors (KIs) are a major class of highly effective anti-cancer drugs.
Unfortunately, therapeutic use of KIs is often associated with cardiotoxicity (CT), a serious adverse condition which limits their use.
This fellowship aims to develop mathematical systems pharmacology models for KI-induced CT.
These models will be used to identify predictive CT signatures that will allow to decrease CT risk of new KIs.
This innovative multi-disciplinary approach consists of integrating mathematical…
UNIVERSITEIT LEIDEN
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ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI NON PROFIT CORPORATION
United States, New York
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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