CORDIS Project
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This project aims to elucidate how oxidants are detected and translated into biological responses in the cardiovascular system. It focuses on thiol-based redox sensors and their role in regulating heart and blood vessel functions during health and disease.
We want to determine how oxidants are sensed and transduced into a biological effect within the cardiovascular system.
The proposed work will focus on thiol-based redox sensors, defining their role in heart and blood vessel function during health and disease.
Although this laboratory has studied the molecular basis of redox signaling for more than a decade, the subject is still in its relative infancy with considerable scope for major advances.
Oxidant signaling remains a ‘hot topic’ with high p…
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