CORDIS Project
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This project aims to develop advanced cardiac organoid models that mimic human heart development and function. By integrating various biological and technological approaches, it seeks to improve disease modeling and drug discovery for cardiovascular diseases, ultimately leading to better therapeutic options.
Cardiovascular disease (CVD) is the leading global cause of death.
Yet, breakthroughs in cardiac therapies are limited due to the poor predictive power of current models.
While the animals fail to accurately replicate human heart physiology, the human pluripotent stem cell-derived models remain underdeveloped and immature for reliable disease modeling and therapy development.
To address these challenges, we propose to further develop our cardiac organoid (“cardioid”) model and recapitulate the k…
INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH
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