CORDIS Project
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This project investigates the mechanisms of myocarditis, an inflammatory heart disease, focusing on the role of immune cells and stromal cells in cardiac tissue. By utilizing advanced models and techniques, it aims to identify new treatment targets and develop antibodies to mitigate cardiac inflammation.
Myocarditis is an acute inflammatory heart disease that can progress to chronic cardiomyopathy and heart failure.
Since there is no specific treatment recommendation available for myocarditis and subsequent inflammatory cardiomyopathy, there is an urgent need to dissect the pathological principles underlying cardiac inflammation and to target those molecular pathways that are at the core of the pathological process.My recent research places cross-reactive CD4+ T cells at the center of inflammato…
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