CORDIS Project
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This project focuses on developing selective ligands for the Neuropeptide Y Y1 receptor, which is linked to breast cancer growth. By utilizing beta-aminocyclopentanecarboxylic acids, the project aims to create stable peptide analogues that can serve as potential anti-cancer drug carriers, enhancing treatment options fo…
Neuropeptide Y (NPY) is a hormone which is the most abundant neuropeptide found in the mammalian central nervous system.
It was proved that NPY is implicated in several highly important biological functions such as food intake, vasoconstriction, orexigenic effects, seizures, anxiety, thermogenesis, cardiac hypertrophy, pain modulation and hormone secretion.
These activities are mediated by six receptors namely:
Y1-Y6.
Recently, it was proved that NPY is also involved in breast cancer growth.
Exp…
UNIVERSITAET REGENSBURG
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