CORDIS Project
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This project investigates the mechanisms of resistance in cancer therapies by analyzing tumor heterogeneity and cancer cell behavior using advanced single-cell technologies. It aims to identify vulnerabilities in drug-tolerant persister cells and develop innovative treatment strategies to improve outcomes for metastati…
Novel cancer molecular-targeted therapies allow to significantly prolong the survival of cancer patients.
However, the inevitable acquisition of resistance mechanisms limits the clinical benefit of these treatments.
To fully understand how resistance develops, it is crucial to better integrate tumor heterogeneity, cancer cell plasticity and microenvironment changes by applying cutting-edge single cell technologies directly on sequentially sampled biopsies from cancer patients.
Additionally, to a…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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France, Villejuif
Type: Research institute
Activity type: Research Organisations
SME: No
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