CORDIS Project
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The CancerPersisters project focuses on understanding persister cells in cancer that evade treatment without genetic mutations. By employing advanced profiling techniques, it aims to identify the mechanisms behind these cells and develop strategies to counteract their resistance to therapy.
Despite tremendous progress in cancer therapy, many patients still succumb to the disease following an initial successful response to treatment.
In addition to the long-appreciated contribution of genetically mutated cells to disease recurrence, persister cells, a rare subpopulation of cells that evade therapy in the absence of any known resistance-mediating mutation, have recently emerged as orthogonal drivers of therapy failure.
While there has been much progress in targeting genetic resistanc…
TEL AVIV UNIVERSITY
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