CORDIS Project
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This project examines how neurons maintain reliable information transfer despite disruptions. Focusing on dopaminergic neurons, it combines electrophysiology and computational modeling to study the dynamic regulation of ion channels and their role in neuronal robustness.
The mammalian nervous system is in some respect surprisingly robust to perturbations, as suggested by the virtually complete recovery of brain function after strokes or the pre-clinical asymptomatic phase of Parkinson’s disease.
Ultimately though, cognitive and behavioral robustness relies on the ability of single neurons to cope with perturbations, and in particular to maintain a constant and reliable transfer of information.So far, the main facet of robustness that has been studied at the neur…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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