CORDIS Project
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This project focuses on understanding the role of microRNAs in cardiac hypertrophy and heart failure. It aims to uncover how these RNA molecules influence signaling pathways and could lead to new diagnostic and therapeutic approaches for heart disease.
Heart failure is a serious clinical disorder that represents the primary cause of hospitalization and death in Europe and the United States.
There is a dire need for new paradigms and therapeutic approaches for treatment of this devastating disease.
The heart responds to mechanical load and various extracellular stimuli by hypertrophic growth and sustained pathological hypertrophy is a major clinical predictor of heart failure. A variety of stress-responsive signaling pathways promote cardiac hy…
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