CORDIS Project
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This project investigates the role of fibroblasts in pancreatic cancer and their contribution to cachexia, a condition causing severe weight loss and muscle wasting. By studying genetic mutations and their effects on fibroblast composition, the research aims to identify potential therapeutic targets for cachexia treatm…
Cancer-associated “cachexia” is a debilitating condition that causes patients to lose weight and muscle, which limits treatment options and worsens survival.
Often patients diagnosed with pancreatic cancer, a lethal and increasingly common malignancy, are affected by cachexia.
Little is known about cachexia and no therapies exist.
It is thus important to identify causes of cachexia to develop treatments.
Pancreatic tumours contain abundant non-cancerous cells, called ""fibroblasts"", that promot…
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