CORDIS Project
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The CADAPIL project focuses on improving drug development by transforming solid-state active pharmaceutical ingredients into liquid salt forms, known as ionic liquids. It aims to create a software tool for the computer-aided design of these compounds, enhancing their bioavailability and addressing challenges in drug fo…
The drug discovery and development process is lengthy, costly, and fraught with high risks, often leading to a low success rate for new chemical entities (NCEs) from discovery through to market approval. A major challenge in advancing many NCEs is their poor bioavailability, primarily dictated by solubility and dissolution rates.
Additionally, the solid-state nature of many drugs introduces the risk of polymorphism, which can adversely affect both development costs and therapeutic efficacy.
An i…
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