CORDIS Project
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This project investigates the role of obesity and specific proteins in the development of bone disease associated with cancers like multiple myeloma and prostate cancer. It aims to identify new therapeutic targets by studying the tumor-bone marrow interactions.
Cancer-associated bone disease is a major cause of morbidity and mortality for patients with the haematological malignancy multiple myeloma, or with skeletal metastases from primary tumours such as prostate cancer.
In order to identify new therapeutic targets, it is necessary to elucidate the complex mechanisms within the bone marrow that promote both tumour growth and the associated bone disease.
There is increasing evidence to suggest that obesity and adipokines are associated with malignancy,…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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