CORDIS Project
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The project aims to elucidate the molecular mechanisms of the complement system, which plays a critical role in immune responses. By investigating how complement interacts with cell membranes, it seeks to provide insights for developing new therapies for related diseases.
Mammalian complement recognizes a variety of cell-surface danger and damage signals to clear invading microbes and injured host cells, while protecting healthy host cells.
Improper complement responses contribute to diverse pathologies, ranging from bacterial infections up to paralyzing Guillain-Barré syndrome and schizophrenia.
What determines the balance between complement attack reactions and host-cell defense measures and, thus, what drives cell fate is unclear.My lab has a long-standing tra…
UNIVERSITEIT UTRECHT
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