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The BrightEyes project develops a novel single-molecule detection technique to observe biomolecules in living cells. This approach enables real-time tracking and analysis of biomolecular dynamics and interactions within their natural environments, overcoming limitations of current methods.
Fluorescence single-molecule (SM) detection techniques have the potential to provide insights into the complex functions, structures and interactions of individual, specifically labelled biomolecules.
However, current SM techniques work properly only when the biomolecule is observed in controlled environments, e.g., immobilized on a glass surface.
Observation of biomolecular processes in living (multi)cellular environments – which is fundamental for sound biological conclusion – always comes wit…
FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
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