CORDIS Project
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The BREAKthrough project aims to combat antimicrobial resistance by making Gram-negative bacteria more susceptible to standard antibiotics. It focuses on developing inhibitors that target the outer membrane of these bacteria, alongside creating a data hub to enhance drug development strategies.
Antimicrobial resistance, which is caused by multi-drug-resistant bacterial pathogens is a global health emergency.
Gram-negative bacteria (GNB) notably hinder effective treatment because of their impermeable outer membrane (OM).
Consequently, many standard-of-care (SOC) antibiotics cannot access intracellular targets in GNB.
The objective of the BREAKthrough European Training Network (ETN) is to sensitise GNB to these antibiotics by making their OM permeable.
To this end, we will develop inhibi…
UNIVERSITE CATHOLIQUE DE LOUVAIN
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Italy, Milano
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Netherlands, Amsterdam
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Slovenia, Ljubljana
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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