CORDIS Project
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The BRAVERY project focuses on developing a novel biocompatible nanocarrier for targeted delivery of neuroactive compounds to the brain. By enabling controlled drug release in response to specific stimuli, it aims to enhance treatment efficacy for neurodegenerative disorders while minimizing neurotoxicity.
Leading to disability and morbidity, neurodegenerative disorders (NDs) have a profound socio-economic impact.
Given the aging of the population, they are raising remarkable concerns.
Several active compounds for NDs treatment showed promising results in-vitro but failed in-vivo due to unfavorable biodistribution and limited biocompatibility.
The nanocarriers (NC) proposed in the last decade have certainly improved brain delivery of active compounds, however, the limited bioavailability of the dr…
ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
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Italy, Trento
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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