CORDIS Project
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This project investigates how acetylcholine signaling in the brain affects cognitive functions like attention and memory. By studying the mechanisms of cholinergic signaling, the research aims to understand its role in cognitive behavior and its implications for conditions like Alzheimer's disease.
Our ability to think, to memorize and focus our thoughts depends on acetylcholine signaling in the brain.
The loss of cholinergic signalling in for instance Alzheimer’s disease strongly compromises these cognitive abilities.
The traditional view on the role of cholinergic input to the neocortex is that slowly changing levels of extracellular acetylcholine (ACh) mediate different arousal states.
This view has been challenged by recent studies demonstrating that rapid phasic changes in ACh levels…
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Netherlands, Amsterdam
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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