CORDIS Project
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The project explores the mechanisms linking neuronal activity, blood flow, and metabolism in the brain. It aims to understand how these interactions affect brain imaging signals and their implications for neuropsychiatric disorders.
The relationship between neuronal activity, blood flow and metabolism provides the basis for the functional brain imaging techniques widely in use today.
Local changes in glucose utilization, oxygen utilization, blood flow and hemoglobin oxygenation are taken as indicators of the activity of neuronal pathways during behavioral tasks or mental states.
Surprisingly however, the cellular mechanisms that underlie the coupling between neuronal activity, cerebral blood flow and metabolism are poorly u…
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