CORDIS Project
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This project focuses on understanding the role of endocannabinoids in brain signaling. By investigating their molecular pathways and effects on synaptic transmission, the research aims to reveal new physiological functions of these lipid messengers in neuronal communication.
We and others have recently delineated the molecular architecture of a new feedback pathway in brain synapses, which operates as a synaptic circuit breaker.
This pathway is supposed to use a group of lipid messengers as retrograde synaptic signals, the so-called endocannabinoids.
Although heterogeneous in their chemical structures, these molecules along with the psychoactive compound in cannabis are thought to target the same effector in the brain, the CB1 receptor.
However, the molecular catalo…
HUN REN KISERLETI ORVOSTUDOMANYI KUTATOINTEZET
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