CORDIS Project
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This project investigates the development of minicolumns in the mammalian cortex, focusing on how signaling pathways like Akt kinase influence cell behavior during cortical formation. Using advanced imaging and genetic techniques, it aims to uncover mechanisms that could lead to new treatments for neuropsychiatric diso…
The mammalian cortex, site of our cognitive functions, is a complex three dimensional environment which develops through an elaborated spatiotemporal choreography. A slight imbalance in this process can lead to devastating pathologies such as autistic spectrum disorders.
While tremendous progress has been made in understanding early cortical development, several questions remain unanswered: how do minicolumns, the basic functional units of the cortex, establish their complex yet highly stereotyp…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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