CORDIS Project
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The project investigates the relationship between gut bacteria and the adaptive immune system in birds. By studying these interactions, the aim is to understand how they affect immunity against parasites and whether these effects can be passed on to future generations.
Mounting an appropriate and effective immune response is critical to protect an organism from infection.
In vertebrates, the adaptive immune system (AIS) plays a central role in immunity, and evidence is accumulating that its development is governed by intricate crosstalk between host immune genes and gut bacteria (GB).
This implies that specific synergisms exist between bacterial taxa and AIS, mainly encoded by the highly polymorphic Major Histocompatibility Complex genes (MHCs), to promote opt…
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