CORDIS Project
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This project explores the role of the extracellular matrix protein tenascin C in breast cancer metastasis, particularly to bone. It aims to understand how tenascin C influences cancer stem cell behavior and to evaluate potential therapeutic interventions targeting this protein.
Metastasis is the spread and outgrowth of cancer cells in organs distant from the site of origin.
In breast cancer, the bone is the most common site of metastasis and metastatic outgrowth in the bone causes hundreds of thousands of deaths world-wide every year.
In recent years it has become evident that stem cell characteristics play an important role in cancer progression and metastasis.
These characteristics are not only intrinsically determined but also maintained and even induced by the micr…
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
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