CORDIS Project
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This project investigates the mechanisms of bone mineralization and remodeling using animal models. It aims to understand how cellular processes affect bone health and pathology, providing insights for potential treatments in bone disorders.
The bone mineralization process is crucial in maintaining the mechanical integrity of bone, from the time of its development to its constant remodeling throughout life.
The process of pathologic mineralization and bone remodeling and how cells control these processes, is very poorly understood in vivo.
By characterizing unique animal models of bone pathologies, spanning both lack and increase of bone, this project will elucidate the process of cell-regulated mineralization during endochondral os…
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