CORDIS Project
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The project investigates paternal genome elimination in mealybugs to understand the mechanisms of genomic imprinting. By studying a unique B chromosome, it aims to reveal insights into epigenetic processes affecting inheritance and potential links to human diseases.
Parent-of-origin effects are considered an important factor in the evolution and development of mammals and plants.
Work on genomic imprinting has primarily focused on these two groups, yet reproduction in thousands of insect species involves an extreme form of imprinting known as “Paternal Genome Elimination”.
In this case, males recognise, silence and, during sperm formation, discard the chromosomes they inherited from their father.
Only the mother’s chromosomes are inherited from the males. T…
THE UNIVERSITY OF EDINBURGH
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