CORDIS Project
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The project explores how genetic variation influences blood cell formation in humans. By analyzing natural genetic differences, it aims to identify key regulators of hematopoiesis, which could improve understanding of blood-related diseases.
The human hematopoietic system is a paradigmatic, stem cell-maintained organ with enormous cell turnover.
Hundreds of billions of new blood cells are produced each day.
The process is tightly regulated, and susceptible to perturbation due to genetic variation.
In this project, we will explore an innovative, population-genetic approach to find regulators of blood cell formation.
Unlike traditional studies on hematopoiesis in vitro or in animal models, we will exploit natural genetic variation to…
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