CORDIS Project
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This project aims to develop human in vitro models of bone marrow to study the interplay between blood and bone tissues. By understanding their mutual influence, the project seeks to identify how regenerative capacities are impaired in diseases and explore novel treatment strategies.
Blood and bone are closely intertwined.
Their intrinsic regenerative capacities are disturbed in many hematological and musculoskeletal diseases.
Re-establishing the regenerative potential is the key to cure these diseases by regenerative medicine.
Multipotent stem cells of both tissues – hematopoietic stem cells (HSCs) for blood and mesenchymal stem/stromal (MSCs) for bone – are the basis for their regenerative capacity.
While it is well established that HSCs are influenced by the bone marrow…
GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER
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Germany, Karlsruhe
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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