CORDIS Project
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This project explores early human embryonic development using blastoids derived from pluripotent stem cells. By employing microfluidic technologies, it aims to study the influence of mechanical cues on blastocyst formation and maturation, enhancing our understanding of embryogenesis and potential fertility treatments.
Early human embryonic development is a complex process characterized by precise cellular interactions and environmental cues.
The blastocyst stage, marked by the formation of the inner cell mass (ICM) and trophectoderm (TE), is pivotal for subsequent embryonic development and implantation.
While mechanical factors are increasingly recognized as influencing cell fate determination, their role in early embryogenesis remains largely unexplored.Human embryo research is fraught with ethical and pract…
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