CORDIS Project
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This project aims to develop innovative bispecific antibodies to enhance cancer treatment, particularly for non-small cell lung cancer. By targeting multiple immune evasion mechanisms, it seeks to improve patient responses to immunotherapy.
Immune checkpoint inhibitors have revolutionized cancer therapy, yet the majority of patients do not respond to current treatments, such as PD-1/PD-L1blockade.
In non-small cell lung cancer (NSCLC), over 70% of patients experience immune evasion mechanisms that prevent effective immune activation.
One such mechanism involves the overexpression of glycans on tumor cells, which can modulate immune responses.
In this project, we propose to develop novel bispecific bi-paratopic antibodies that simul…
ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS
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