CORDIS Project
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This project leverages bacteriophages to develop innovative synthetic biology tools for manipulating bacterial functions. It aims to create designer bacteria for applications in industrial processes and vaccine development by utilizing phage-encoded genetic circuits.
As nature’s first bioengineers, bacteriophages have evolved to modify, adapt and control their bacterial hosts through billions of years of interactions.
Indeed, like modern synthetic biologists aspire to do, bacteriophages already evade bacterial silencing of their xenogeneic DNA, subvert host gene expression, and co-opt both the central and peripheral metabolisms of their hosts.
Studying these key insights from a molecular systems biology perspective, inspired us to develop these evolutionary…
KATHOLIEKE UNIVERSITEIT LEUVEN
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