CORDIS Project
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This project investigates the mechanisms of protein transport across biological membranes using computer simulations. It focuses on three key proteins: SecA, a motor protein in bacteria; the AHA2 proton pump in eukaryotes; and channelrhodopsin-2, a light-gated cation channel, to enhance understanding of their roles in…
Living cells depend on the correct functioning of proteins that transport cargo across the membranes.
We will use computer simulations to understand the mechanisms employed by three proteins that mediate transport across biological membranes.
Each of these three proteins is important for physiology and disease.A large part of the research planned aims at understanding the SecA motor protein.
SecA is an essential component of the Sec translocation system in bacteria, where it couples the hydroly…
FREIE UNIVERSITAET BERLIN
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