CORDIS Project
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This project aims to understand the organization of protein filaments within cells, which is crucial for cell mechanics and related diseases. By analyzing disordered filament structures, it seeks to uncover the principles governing their behavior and implications for cell movement.
Protein filaments and their geometrical organization are crucial for cell mechanics, and their failure is related to diseases ranging from sickle cell anemia to Alzheimer’s to cancer.
While such stakes would suggest a well-defined design to the engineer, sub-cellular filamentous structures are often surprisingly disordered, and very variable from one cell to the next.
Physically, this disorder can be traced back to complicated random aggregation processes involving particles with intricate struc…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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