CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the regulation of deubiquitinases, specifically the A20-family of ovarian tumor deubiquitinases, to understand their role in cellular processes like signaling and tumorigenesis. It employs techniques such as X-ray crystallography and electron microscopy to explore protein interactions and stru…
Ubiquitination is a reversible post-translational modification (PTM) regulating diverse cellular functions including cell cycle, apoptosis, gene expression, inflammation and DNA repair.
Ubiquitination results in the tagging of proteins with either monoubiquitin or polyubiquitin chains of different linkages that are structurally distinct.
Given that protein ubiquitination is involved in so many cellular processes, it needs to be under very tight regulation.
Protein ubiquitination is reversed by d…
MEDICAL RESEARCH COUNCIL
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
