CORDIS Project
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BIOCHIP aims to treat knee cartilage injuries using engineered grafts from nasal chondrocytes, which have shown better cartilage regeneration potential. The project includes a clinical trial to evaluate the effectiveness of these grafts in improving patient outcomes.
Spontaneous healing of articular cartilage injuries is poor and untreated defects predispose to osteoarthritis.
Current therapies, including innovative autologous cell-based treatments, cannot predictably and reproducibly restore cartilage structure and function. BIOCHIP will carry out a multicenter, prospective phase II clinical trial to treat knee cartilage injuries using engineered grafts based on autologous nasal chondrocytes (NC).
As compared to typically employed articular chondrocytes, NC…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Switzerland, Basel
Type: Public body
Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
SME: No
Germany, Freiburg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Croatia, Zagreb
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Croatia, ZAGREB
Type: Research institute
Activity type: Research Organisations
SME: No
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