CORDIS Project
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This project investigates how cells interact with a newly developed synthetic gel that mimics the extracellular matrix. By studying the mechanical properties of this gel and its effects on cell behavior, the research aims to enhance understanding of cellular responses to mechanical forces, which is crucial for various…
Cells continuously sense external forces from their microenvironment, the extracellular matrix (ECM).
In turn, they generate contractile forces, which stiffen and remodel this matrix.
Although this bi-directional mechanical exchange is crucial for many cell functions, is remains poorly understood, mostly since the majority of ECMs, both natural and synthetic, are difficult to control or lack biological relevance. A new synthetic polyisocyanide (PIC) gel is the first material that is an excellent…
KATHOLIEKE UNIVERSITEIT LEUVEN
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