CORDIS Project
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This project aims to enhance genetic diagnostics by utilizing optical DNA mapping technologies to analyze long individual DNA molecules without amplification. It addresses challenges in detecting genomic variations and epigenetic markers, focusing on applications in cancer diagnosis and bacterial infections.
Cytogenetic diagnostic approaches provide information on the single-chromosome level but suffer from low resolution and throughput.
In contrast, next generation sequencing (NGS) based diagnostics provides single base resolution and high throughput but suffer from short reads that prevent analysis of large genomic aberrations as well as being prone to PCR-amplification bias and erasure of epigenetic information.
This proposal aims to bridge the gap between these domains by analyzing long individu…
TEL AVIV UNIVERSITY
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Sweden, Goteborg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Sweden, Lund
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Israel, Haifa
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Belgium, Leuven
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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