CORDIS Project
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This project focuses on a novel in vivo approach for assessing pancreatic islet function in diabetes treatment. By transplanting islets into the eye of mice, it enables non-invasive monitoring of β-cell health, aiming to validate new diabetes drugs effectively.
Validation of an in vivo translational medicine approach for the treatment of diabetes and diabetes complications To develop new drugs for treatment of diabetes, there is an immediate need for an in vivo approach allowing the assessment of β-cell function and survival in the living organism non-invasively, longitudinally and at single-cell resolution.
We therefore transplant pancreatic islets into the anterior chamber of the eye (ACE) of mice for functional microscopic imaging.
In the ACE islets…
KAROLINSKA INSTITUTET
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