CORDIS Project
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This project investigates the dysfunction of pancreatic beta cells and brown adipose tissue in diabetes, particularly in the context of obesity. It aims to identify molecular pathways and develop organelle therapy to restore cellular function and improve metabolic health.
A reduction in functional pancreatic beta cell mass is the key feature of type 1 and type 2 diabetes.
Beta cell failure is exacerbated in the context of obesity and insulin resistance.
Brown adipose tissue (BAT) is a highly metabolic organ, mediating energy dissipation and glucose disposal, thus contributing to maintain energy balance. BAT dysfunction contributes to obesity and impaired glucose metabolism, increasing functional demand on the beta cells.
The cellular dysfunction of beta cells and…
UNIVERSITE LIBRE DE BRUXELLES
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom, Cambridge
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Switzerland, LAUSANNE
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Spain, Barcelona
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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