CORDIS Project
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This project explores the role of gut bacteria in the inflammation and dysfunction of insulin-producing cells in type 2 diabetes. It aims to identify specific bacteria that contribute to disease progression and test their effects in a mouse model.
Type 2 diabetes (T2D) has risen to epidemic proportions resulting in major morbidity and mortality.
In addition to insulinresistance (i.e. impaired insulin action), impaired function and destruction of the insulin-producing beta cells form the directcause for hyperglycemia and T2D, and causes the progressive course of disease.
As such, due to continuous beta-celldestruction, many patients require treatment with exogenous insulin therapy.
Clearly, therapies that may halt or reverse thisdetrimenta…
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Canada, Vancouver
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Netherlands, Amsterdam
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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