CORDIS Project
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This project investigates the mechanisms behind the extreme radiation resistance of the bacterium Deinococcus radiodurans. By studying specific proteins involved in DNA repair, the research aims to understand how this organism maintains genome stability under high radiation exposure.
Deinococcus radiodurans (DEIRA) is an extreme radiation and desiccation resistant bacterium, which tolerates radiation doses up to 5000 Grays without loss of viability.
The mechanism of this outstanding resistance is not known, but is probably a result of efficient genome packing, cell structure and DNA repair.
For ten years the fellow has studied structure/function relations of proteins in the Base Excision Repair (BER) pathway from DEIRA, in order to determine their role for the extreme radiat…
INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA
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