CORDIS Project
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This project investigates how B cells activate and produce antibodies against pathogens, focusing on the role of mechanical forces in antigen binding and internalization. The aim is to improve understanding of B cell responses to infections, which could inform vaccine design.
The production of antibodies against pathogens is an effective mechanism of protection against a wide range of infections.
However, some pathogens evade antibody responses by rapidly changing their composition.
Designing vaccines that elicit antibody responses against invariant parts of the pathogen is a rational strategy to combat existing and emerging pathogens.
Production of antibodies is initiated by binding of B cell receptors (BCRs) to foreign antigens presented on the surfaces of antigen…
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IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom, LONDON
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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