CORDIS Project
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This project investigates the genetic basis of mood disorders using a large Brazilian family with a high incidence of these conditions. By analyzing genetic variations and their impact on mood disorders, the research aims to enhance understanding and treatment of bipolar and major depressive disorders.
This proposal describes my aim to use a uniquely large multigenerational family to better understand the genetic underpinnings of mood disorders: the Brazilian Bipolar Family (BBF).
The family has a high incidence of mood disorders, featuring diminishing age of onset over generations and assortative mating, whereby many of the marriages in the family are between individuals with a psychiatric disorder.
Mood disorders are leading contributors to the global burden of disease.
Bipolar disorder is c…
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