CORDIS Project
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This project investigates enteroviruses, which are significant human pathogens causing various diseases. It aims to deepen understanding of the virus life cycle and host interactions to develop broad-spectrum antiviral drugs, focusing on the role of cellular condensates in antiviral signaling.
The genus Enterovirus comprises many important human pathogens (e.g. polio-, coxsackie-, and rhinovirus) that cause a wide array of diseases ranging from mild to life-threatening.
As there are hundreds of enteroviruses and vaccination to all of these is not feasible, there is an unmet need for pan-enterovirus antiviral drugs.
Hence, we need to deepen our knowledge on the enterovirus life cycle and virus-host interactions.
Mammalian cells express an arsenal of sensors that function to restrict vi…
UNIVERSITEIT UTRECHT
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